By S Narasimha Murthy, Howard I. Maibach
Discussing present options, ongoing study, new methods, and simple strategies within the therapy of nail illnesses, Topical Nail items and Ungual Drug supply summarizes the present wisdom and represents a jumping-off aspect for developing novel options of drug supply around the nail.
A becoming sector of pharmaceutical learn, the hunt for effective supply recommendations that may pass the nail barrier has yielded numerous potent techniques, introduced jointly during this book.
- Nail anatomy, body structure, illnesses, and treatment
- Permeability of the nail plate
- Topical nail formulations
- Approaches to augment ungual and trans-ungual drug delivery
- In vitro and in vivo versions to guage topical nail formulations
- Nail sampling techniques
- Bioengineering of the nail
- Trans-ungual iontophoresis
- Pharmacokinetics of substances within the nail apparatus
- Onychopharmacokinetics: proposed version insight
- Photodynamic treatment of nail diseases
- The nail as a surrogate for investigating drug use
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Additional info for Topical Nail Products and Ungual Drug Delivery
A steep gradient in drug concentrations within the nail plates has been found from the dorsal nail surface (that was previously in contact with the drug formulation) toward the inner nail (Hui et al. 2002). Low (or no) drug presence in the deeper parts of the nail prevents fungal eradication and cure. It should also be noted that the MICs of drugs is most often measured in standard media—a very different environment to the nail plate. The presence of keratin is known to increase the MICs (Osborne et al.
Spearman. 1966. ” Archives of Dermatology 94 (5): 652–57. Jemec, G. B. , T. Agner, and J. Serup. 1989. ” British Journal of Dermatology 121 (4): 443–46. 32 Topical Nail Products and Ungual Drug Delivery Jemec, G. B. , and J. Serup. 1989. ” Archives of Dermatology 125 (5): 643–46. Jiaravuthisan, M. , D. Sasseville, R. B. Vender, F. Murphy, and C. Y. Muhn. 2007. ” Journal of the American Academy of Dermatology 57 (1): 1–27. , J. S. Comaish, and S. Shuster. 1991. ” British Journal of Dermatology 125 (1): 27–29.
And G. E. Pierard. 2003. ” Dermatology 207 (3): 255–60. Baden, H. , L. A. Goldsmith, and B. Fleming. 1973. ” Biochimica et Biophysica Acta 322 (2): 269–78. , M. Feuilhade, A. Datry, S. Goettmann, P. Pietrini, C. Viguie, G. Badillet et al. 2000. ” British Journal of Dermatology 142 (6): 1177–83. , A. K. Gupta, and G. E. Pierard. 2005. ” Expert Opinion on Pharmacotherapy 6 (4): 609–24. , R. J. Hay, and J. I. Garduno. 2008a. ” Journal of Dermatological Treatment 19 (2):72–81. , R. J. Hay, and J.