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By Frank J. Dixon (Eds.)

This quantity contains the cumulative topic index for volumes 37 to sixty five of the "Advances in Immunology" sequence.

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45:116 peptides, 45:138 polymorphic residues, 45:158, 159, 162 structure-function relationships, 45:136, 140 T cell repertoire, 45:165 T cell subsets and, 41:40 cell surface molecules, 41:44 H-2 alloantigen recognition, 41:78-83 H-2 molecules in thymus, 41:100-102 H-2-restricted antigen recognition, 41:68 Allospecificities, NK-defined, genetic analysis, 55248-349 Allotype complement receptor 1 and, 46:185, 187-190. 195, 196 iiiiii)i~~iosenescence and, 46248 a# heterodimer receptor structure, 42:168 a chain, 43:282, 284-287 free, retention of, 52:63-64 IgA, structure and function, 40:155- 158 11,-2 cell division and, 423173 growth sipal, 42:172-173 a enhancer, T cell receptor gene, 43:268 Alpha helix, amphipathic, 43:204 Alternate antigen pathway, and trapping of iinniinie complexes, 51:265-269 Alternative complement pathway antibodies as activators, 51:28-29 particulate activators, 38:384-386, 392 Aluni djrivant adsorbed MAP, 60:141 HIV V3 loop in, 60:131 with liposonie-lipid A, MAP in, 60:112 (TlB), MAP in, 60:117-118 Al ti nilBorderefkz pertussis (AB P), 46: 137 Alveolitis CD23 antigen and, 49:160 extrinsic allergic, 62:267 Alzliriiner’s disease catises, 66:2130-261 and IL-6, 54:42-43 Amino acids antibody diversity and, 42:97 antigenic equivalence, 43:68-72 antigen-presenting cells and, 47:60, 66, 89 antinuclear antibodies and, 44:106, 108, 125, 129-131 8 SUBJECT INDEX Amino acids (contintred) autoimmune demyelinating disease and, 49:358, 363, 366, 368 autoimmune thyroiditis and, 46:317 antigens, 46:268, 272 genetic control, 46:284 humoral responses, 46:302 prevention, 46:315, 316 B cell formation and, 41:197, 198 CD1 proteins, 59:ll-22 CD4 niolecules and, 44:285, 286, 289, 292 295, 296 CD5 B cell and, 47:145, 146 CD8 molecules and, 44:272-276, 278 CD23 antigen and, 49:156, 162-166 complement receptor 1 and, 46:184, 186, 187, 194 complement receptor 2 and, 46:202, 205, 210 conservation, 43:115, 221-222 contact residue, 43119 critical residue, 43:67-68 critical to binding energy, 43:24 cytolysis and, 41:285 cytototoxic T cells and, 41:135, 170 µglobulin.

59:39-43 CD2, role in T cell death, 58:226 CD3, IGF-I-H, 63:403 CD4 molecules and, 44:297, 300 CD5 B cell and, 47:161, 162 Ig gene expression, 47:150-154, 157, 158 lineage, 47:129 marker for activation, 47:127 physiology, 47:130, 131, 133, 135-137, 139. 5 expression regulation, 49: 159 FceHII, 49:165 CD40, 52:188-191 and anti-IgM, costimulatory effect on B cell proliferation, 52:190 CD59. 1, induction of thymic cell depletion, 58:274 Fab Kol, crystal packing, 43:19-20 Fab region, 43:s-9 Fab structures, 43:17 Fc region, 43:8-9 genetically engineered, see Genetically engineered antibodies glycoprotein, phase I clinical trials, 40:366-370 helper T cell cytokines and cross-regulation of differentiation, 46:131, 132 differential induction, 46:127, 129, 130 functions, 46:116, 118-120 immune responses, 46:133, 137, 138 precursors of differentiation states, 46:124 HIV-1 immunity, 63:97-98 HIV infection and immune response, 47:405-410 inimunopathogenic mechanism, 47:388, 389, 393, 395,398 neuropsychiatric manifestations, 47:404 human, from combinatonal libraries affinity, strategy for improvement, 57:263-266 allergens, 57:228 amino acid sequences analysis, 57:233-238 RGD, 57:261-263 bacteria, 57:228 cloning strategies, 57:203-206 design, 57:261-263 Epstein-Barr virus-transformed cell linederived, 57:229-230 expression of antibody fragments, 57:207-208 to Graves' ophthalmopathy self-antigens from human donors, 57:245 to HIV-1 self-antigens from human donors, 57:246-250 HuSCID mouse-derived, 57:230-231 hybridomas, 57:229-230 immune donors, 57:208-242 naive repertoire approach, 57:250-252 overview, 57:191-192 phage display antibody fragments, 57:195-198 vector systems, 57:199-203 to primary biliary cirrhosis self-antigens from human donors, 57:244-245 primate-derived, 57:231-232 principles of cornbinatorial approach, 57:192-195, 266-267 selection strategies, 57:206-207, 261-263 staphylococcal protein A, 57:229 study of responses, 57:232-242 synthetic repertoire approach, 57:250, 252-260 to thyroid disease self-antigens from human donors, 57:242-244 viruses, 57:209-228 cytomegalovirus, 57:220-221 hepatitis B virus, 57:220 herpes' simplex virus type 1, 57~222-227 herpes simplex virus type 2, 57:222-227 HIV-1, 57:211-217 measles, 57:227-228 SUBJECT INDEX respiratoiy syncytial virus, 57:2 17-2 19 varicella Zoster virus, 57:221-222 whole antibody inolecules, 57:208 human antichimeric, 64:323-324, 330 Iiunian anti-moiise, 64:323 irnninne response, chemotherapy limited by, 56:304.

44:187 13 IL-6. 66:132 clinical applications, 54:50 iiiiiiiuiiosetiesceiiceand, 46:221, 253 lymphocyte activation, 46:222 inucosal immunity, 46:252 regulatory changes, 46:247, 248, 250, 25 1 stein cells, 46:246 induced coinplementarity, 43:16-20 ininiunological, biochemical and crystallographic data, 43:16-18 mobility data, 43:20 vanalde domain structure superposition, 43:18-20 to Leu7, 42:191-192 leukocyte integrins and, 46:164 lung, 59:393-394, 411-412 lyrnpliocyte homing and high endothelial venules, 44:317, 318 ininiiine response, 44:330-332, 335 niolecules, 44:342-344, 346, 350, 352 regional specificity, 44:326.

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